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Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), announced today positive results from the Phase III evERA Breast Cancer study. Data showed giredestrant in combination with everolimus significantly reduced the risk of disease progression or death (progression-free survival; PFS) by 44% and 62% in the intention-to-treat (ITT) and ESR1-mutated populations, respectively, compared with standard-of-care endocrine therapy plus everolimus. The evERA study is evaluating the investigational giredestrant combination in people with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer previously treated with cyclin-dependent kinase (CDK) 4/6 inhibitor and endocrine therapy. This is the first positive head-to-head Phase III trial investigating a selective estrogen receptor degrader-containing regimen versus a standard-of-care combination. The results are being presented in an oral session at the European Society for Medical Oncology Congress 2025. Data will be shared with health authorities, with the aim of bringing this potential treatment option to people as soon as possible.

Analyst Jake Reynolds is officially launching Phase Two of the Alliance Trading Program Our SIG Chicago quantitative trading room has officially launched the second phase of the Alliance Trading Program. The goal is to demonstrate and verify a minimum return of 30% and a maximum return of 137% by the end of December 2025, with profits varying based on each participant’s invested capital. This program primarily assesses the execution and cohesion of all WhatsApp group members while screening out any unidentified participants.

Analyst Nathan Caldwell is officially launching Phase Two of the Alliance Trading Program

Kingsy Store announces updates to the KingsyFit™ home gym ab workout trainer, now featuring five adjustable resistance levels and an enhanced foldable design.

Wireless technologies are transforming how people connect, communicate, and use the internet. Strong and reliable connections are becoming increasingly prevalent in daily life thanks to cell phones and emerging technologies like AR and VR. The most significant aspect of this shift is human-centred wireless engineering, which ensures that radio frequency technology functions properly in practical settings and considers human behaviour into account.

Hongkong, China, October 18, 2025 -- Next-generation digital finance platform MPChat today released its foundational manifesto, "The Fourth Covenant: MPChat’s Manifesto for Digital Freedom" officially declaring its commitment to solving the growing issues of privacy erosion and value-flow barriers in the current digital world. By seamlessly integrating end-to-end encrypted communication, a versatile stablecoin wallet, and a global payment card into a single super-application, MPChat aims to provide a truly sovereign digital life solution for global users, especially digital nomads, international students, and AI developers.

Broker Greg Gunter celebrates 5th anniversary of opening the first Berkshire Hathaway HomeServices office in Mexico, offering unparalleled expertise to American expats seeking luxury homes in San Miguel de Allende.

Angie Cain, a nurse, neuroscience coach, and women’s health advocate, has been selected for the “Fab Over 40” Fundraiser supporting the National Breast Cancer Foundation. Her mission empowers women through neuroscience, and she plans to donate her winnings to support domestic violence survivors' education.

Author Michael Galileo launches his book Where Time Comes From and unique Real Time Earth Clocks to help individuals understand time, reality, and human choice.

NannyCity, a trusted nanny service provider, offers personalized nanny placements and support for working parents across the USA, helping families balance work and childcare.

Tacitous and NKM4You announce a new initiative focused on preserving critical expertise in high-risk industries facing a knowledge retention crisis as workers retire.

Proprietary AI identifies off-market acquisition targets using firmographic and intent data—bringing institutional-grade sourcing to private investors.

Singapore, October 18, 2025 -- Global cryptocurrency exchange platform Zoomex today announced that Argentine football star Emiliano Martínez has officially become the platform’s Global Exclusive Brand Ambassador . This collaboration marks a significant milestone in Zoomex’s international strategy in the “Sports × Web3 Innovation” field, aiming to connect the spirit of sports with the world of digital assets through speed, precision, and an exceptional user experience.

As traditional markets fluctuate, A&E Watches reminds buyers that a Rolex is both a luxury and a lasting asset.

The company’s new Orlando presence will support regional clients and accelerate adoption of AI-powered marketing solutions across the Southeast.

Helping Bay Area Homeowners Embrace ADUs as Smart, Sustainable Housing Solutions

New York, US, October 18, 2025 -- Associated Wealth Advisors Ltd (AWA), a trailblazing fintech leader revolutionizing global wealth management, has unveiled “The 10-Billion Fund Showdown,” a landmark global investment event designed to select an exceptional leader for its transformative The 10-Billion Fund project. Dubbed the “Olympics of Capital Markets,” this high-profile competition underscores AWA’s dominance in fintech innovation and inclusive finance, while paving the way for its anticipated Nasdaq listing in May 2026.

Houston residents are exploring private health insurance options to ensure access to quality care amidst evolving policies. With various plans available, individuals and families seek expert guidance to align coverage with health and financial priorities for peace of mind.

The functional beverage market has long been dominated by two camps: sugar-laden sports drinks promising hydration, and artificially sweetened alternatives that compromise on ingredients.

Supporting families across Northern California, AAA Water Systems is helping parents provide cleaner water for their kids as they head back to school.

Shawn Maldon’s journey from political turmoil to leadership success inspired his Blueprint for Comeback, empowering leaders through The Maldon Academy. Turning loss into a legacy of resilience, his story shows how overcoming adversity can ignite purpose, strengthen leadership, and transform challenges into lasting impact.

Throughout his career, he has remained a considerable financial contributor towards both national charitable organizations and to local non-profits in the eastern Tri-State area.

Deepening the strategy, Mr. Amaradio acknowledged the concept that wealth is entrusted to man by God, and as such, belongs to Him, providing good reason to be generous with gifts to charitable causes.

For a time, brands were able to get eyeballs by relying primarily on content, video, and influencer marketing, but as consumer behaviors kept changing and new platforms gained popularity, they were forced to consider formats that would minimize intrusion while promoting engagement, Daniel Yomtobian comments.

The MAS Holdings-backed manufacturer continues to redefine how apparel supports women’s wellbeing through science-led design and advanced textile engineering.

MEXICO CITY, Oct. 17, 2025 (GLOBE NEWSWIRE) -- Grupo Aeroméxico, S.A.B. de C.V. (“Aeroméxico”) today announced the launch of its global offering (the “Global Offering”), consisting of 11,727,325 American Depositary Shares (“ADSs”) in the United States and 27,463,590 common shares in Mexico. Each ADS represents 10 common shares of Aeroméxico.

Please replace the release dated October 15, 2025 with the following corrected version due to multiple revisions.

NAPERVILLE, IL / ACCESS Newswire / October 17, 2025 / In the layered silence between recorded history and lived truth, some voices vanish; and others fight their way back through time. Thomas Kline, 's Tommy Cassidy: An Irish Slave in America - Protector of Alexander Hamilton resurrects one such voice: an Irish child sold into bondage whose path entwines with the young Alexander Hamilton. What emerges is both a historical revelation and an act of narrative defiance.

Light & Wonder, Inc. (NASDAQ and ASX: LNW) (“Light & Wonder,” “L&W,” “we” or the “Company”) is providing an update on today’s ruling from the Nevada Court regarding the ongoing litigation with Aristocrat.

U-Haul® Company of Alaska has made all of its 11 Company facilities across the state available to provide 30 days of free self-storage and U-Box® container usage to support displaced residents after Typhoon Halong destroyed many Native communities along the western coast.

Gables, FL - Pest Brothers, a licensed and insured pest control company, is proud to announce the launch of its environmentally friendly pest control services in South Florida, including the Gables area. The company, founded in 2023 by brothers Jose and Michael Rodriguez, offers comprehensive pest protection solutions designed to keep homes safe while prioritizing environmental sustainability. With a focus on excellent customer service, fast response times, and affordable pricing, Pest Brothers is committed to providing effective pest control Gables FL treatments that are both safe and environmentally responsible for homeowners in the Gables and surrounding areas.

Fitchburg, WI - Terminator Pest Control Company, a leader in professional pest control in Fitchburg, WI, is proud to announce its commitment to providing eco-friendly, sustainable pest control solutions for homes and businesses in Fitchburg and the surrounding areas. By utilizing advanced, environmentally responsible techniques, Terminator Pest Control is setting a new standard for pest control that prioritizes safety, health, and the environment without sacrificing effectiveness.

Oklahoma City, OK - Emergency plumbing calls have been on the rise throughout Oklahoma, with homeowners and businesses facing a variety of plumbing issues due to seasonal changes, weather-related stressors, and aging infrastructure. A+ Plumbing & Gas, one of the best plumbing companies OKC, is shedding light on the top causes for these surges and offering expert tips on how to avoid emergency plumbing situations.

Norman, OK - Thunder Pest Control, a trusted provider of Norman pest control, is proud to announce the launch of its new Community Pest Safety Initiative. This program aims to educate residents of Norman and surrounding areas about the importance of pest control, offering expert advice and affordable solutions to protect homes and businesses from pests and the health risks they can carry.

Listen to the interview on the Business Innovators Radio Network: https://businessinnovatorsradio.com/interview-with-chris-dixon-with-oxford-advisory-group-discussing-taxes-estate-plans/

Kolibri Global Energy Inc. (the “Company” or “Kolibri“) (TSX: KEI, NASDAQ: KGEI) wishes to provide an update to certain information contained in the management information circular and related materials (the “Circular”) filed on October 15, 2025 in connection with a special meeting of shareholders (the “Meeting”) called by the Company in response to a shareholder requisition made on behalf of TFG Asset Management UK LLP, the purpose of which is to vote on altering the Notice of Articles of the Company to cap the number of common shares of the Company (“Shares”) that the Company is authorized to issue at 37,367,894 (the “Proposed Resolution”).

Smart Separation, a Toronto-based provider of alternative dispute resolution, is helping couples navigate separation and divorce through confidential, solution-focused family mediation in Toronto . Led by founder Assad Bajwa, a Toronto family mediator known for a calm, practical approach, the firm guides parents and partners toward clear, durable agreements without the cost and stress of litigation.

News Release Highlights

The Law Offices of Frank R. Cruz announces an investigation of MoonLake Immunotherapeutics (“MoonLake” or the “Company”) (NASDAQ: MLTX) on behalf of investors concerning the Company’s possible violations of federal securities laws.

Law Offices of Howard G. Smith announces an investigation on behalf of MoonLake Immunotherapeutics (“MoonLake” or the “Company”) (NASDAQ: MLTX) investors concerning the Company’s possible violations of federal securities laws.

LOS ANGELES, CALIFORNIA / ACCESS Newswire / October 17, 2025 / Regenesys, a leader in strategic LinkedIn growth systems and organic inbound lead generation, today announced the upcoming launch of its automated multi-channel social media tool, designed to help B2B brands achieve measurable growth and authority on LinkedIn and beyond.

Glancy Prongay & Murray LLP, a leading national shareholder rights law firm, today announced that it has commenced an investigation on behalf of MoonLake Immunotherapeutics (“MoonLake” or the “Company”) (NASDAQ: MLTX) investors concerning the Company’s possible violations of the federal securities laws.

Montreal, Canada - October 17, 2025 - Future Electronics, a leading global distributor of electronic components, is proud to announce the launch of a new digital campaign spotlighting Micron's industry-leading DRAM and NOR flash memory portfolio designed to accelerate innovation across demanding markets.

P.S., the tech-forward greeting card company created by a team of innovative college students, has launched an exciting new feature. Now, users can take advantage of an all-new hyper-personalization feature that allows users to select any card on the P.S. website and instantly make it their own.

Arizona’s hottest new trend just got cooler. Frosty Cactus Margarita & Slushy Machine Rentals has partnered with A Perfect Party Rental to launch Frozen Dirty Soda Parties —a refreshing, alcohol-free twist perfect for birthdays, weddings, and corporate events across the East Valley.

Author Jonathan D. Nichols invites readers into the heart of Halloween with Witches and Pumpkins, Fur and Fangs, a gripping new collection of twenty interwoven stories that capture the eerie essence of the season. As the veil between the living and the dead grows thin, Nichols’ book celebrates the darker delights of October with monsters, ghosts, witches, and creatures that lurk just beyond the glow of a jack-o’-lantern.