GNC Holdings downgraded


Goldman Sachs downgraded GNC Holdings Inc. (NYSE: GNC) from a Neutral rating to a Sell rating sending the stock price plummeting $1.89 to close at $9.26.

Rent-A-Center Inc. (Nasdaq: RCII) reported a sharp 14% drop in fourth quarter same store sales at its Core U.S. stores and warned that revenue would fall short of previous guidance. The stock price tumbled $1.88 to close at $8.31.

DryShips Inc. (Nasdaq: DRYS) announced a 1-for-8 reverse stock split sending the stock price tumbling 58 cents to close at $1.01.

Catabasis Pharmaceuticals Inc. (Nasdaq: CATB) published positive results from a Phase 1 study of its Duchenne muscular dystrophy treatment edasalonexent in the Journal of Clinical Pharmacology. Shares of the biopharmaceutical gained 82 cents to close at $4.97.

Ocular raises outlook


Ocular Inc. (Nasdaq: OCLR) raised its second quarter revenue forecast lifting the stock price up $1.35 to close at $9.48.

Rumors circulated that outgoing Canadian Pacific Railway Ltd. (NYSE: CP) chief executive Hunter Harrison may be headed to CSX Corp. (Nasdaq: CSX). Shares of Canadian Pacific Railway soared $5.09 to close at $150.31while CSX stock leaped $8.63 to close at $45.51.

Uni-Pixel enters MOU


Uni-Pixel Inc. (Nasdaq: UNXL) entered a Memorandum of Understanding with General Interface Solution to form a three year strategic manufacturing project. The stock price gained 43 cents to close at $1.69.

The Food and Drug Administration granted Fast Track designation to aTyr Pharma Inc.'s (Nasdaq: LIFE) limb girdle muscular dystrophy treatment Resolaris. Shares of the biotherapeutics company climbed 80 cents to close at $3.25.

Cameco Corp. (NYSE: CCJ) reported preliminary 2016 earnings that missed analyst estimates by a wide margin and announced job cuts. Shares of the uranium producer plunged $2.42 to close at $10.85.

Gigamon warns of shortfall


Gigamon Inc. (NYSE: GIMO) warned that fourth quarter revenue would fall short of expectations sending the stock price plummeting $12.65 to close at $31.40.


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