Closing Bell Report

The markets closed mixed as crude oil prices rose again while consumer confidence tumbled.  The Dow climbed 43 points to 12,892 while Nasdaq lost 6 points to 2423.

On the upside

Shares of Progenics Pharmaceuticals (Nasdaq: PGNX) continued to climb after the FDA approved its opiate induced constipation treatment Relistor.  The biopharmaceutical also announced plans to repurchase up to $15 million in common stock

Fannie Mae (NYSE: FNM) reported that its mortgage commitments rose in March to $31 billion from $25 billion the previous month.

First quarter earnings for Trimble Navigation (Nasdaq: TRMB) surged to beat estimates as revenue climbed.

On the downside

MEMC Electronic Materials (NYSE: WFR) swung to a loss for the first quarter and forecast second quarter results below estimates due to problems at one of its manufacturing plants.

Horizon Lines (NYSE: HRZ) blamed record fuel prices, a drop in traffic to Puerto Rico and severe weather in Alaska for sharply lower first quarter earnings.  The shipping and logistics company also cut its full year guidance.

NBTY (NYSE: NTY) reported second quarter earnings that dropped to fall far short of analyst expectations as costs soared.

In the broad market, advancing issues outpaced decliners by a margin of more than 5 to 3 on the NYSE and by 9 to 7 on Nasdaq.  The Russell 2000 which tracks small cap stocks added 5 points to 722.